Pomegranate: Our miracle heart cure?
Filed under: Diet, Prevention
It's something you don't often eat but you probably should because it's chalk-full of antioxidants and other healthy good stuff: Pomegranates. The fruit benefits your cardiovascular system, and also has been shown to help with Alzheimer's, cancer and even erectile dysfunction. And it's a better source of flavonoids than red wine, green tea or blueberry juice. And the best news is, you don't have to buy that expensive juice at the supermarket -- chances are you can grow pomegranates in your backyard. It's a fairly low-maintenance plant. To learn more about the pomegranate, check out Wikipedia.
History underway in type 1 diabetes cure
Filed under: Type 1, Childhood, Research, Events, Support
Dr. Faustman's lab is currently collecting blood samples from individuals with established Type 1 diabetes. These samples are being used to quantify the number of autoreactive T-cells and develop the adequate dosage for Phase 1 of human trials to cure Type 1 diabetes.
The research has been presented and the NIH confirmed it. By reeducating the confused T-cells and instructing them not to attack healthy islets, an apparent cure of established type 1 diabetes in non-obese diabetic mice is possible. Now, Dr. Faustman is collecting human samples to bestow the same cure for diabetes in humans.
If you wish to be a part of this revolutionary event for curing Type 1 diabetes, please contact the Clinical Coordinator or call Dr. Faustman's lab at (617) 726-4084. Each participant is asked to bring a control person along with them - an unrelated person without Type 1 diabetes or another autoimmune disease. Diabetic or not - you can be a part of history in curing Type 1 diabetes!
Two Presidential Candidates Announce Plans to Cure Diabetes
Filed under: Type 1, Type 2, Childhood, Adult Onset, Research, Daily News, Events, Support
Did anybody catch the first ever YouTube democratic debate last week? It was cosponsored by CNN and the cool thing about it was this: all the questions came in from Americans like you and me. Turns out two of the candidates spoke out on behalf of diabetes. Here's what they had to say...
Governor Richardson mentioned the fact that 33% of Medicare is wrapped up in diabetes costs. He suggests, "Let's have major prevention programs, and also ways that we can ensure that we find a cure." He still has not announced a plan to ensure a cure. But if he does - I'm willing to bet all of his campaign funding from Big Pharma might mysteriously disappear.
The other candidate addressing diabetes was Senator Chris Dodd of Connecticut. Dodd's promise came after from a woman's question about stem cell research. Somehow the senator was able to plug an endeavor to "deal with diabetes". However, much like Governor Richardson - he has yet to announce a plan to cure. Politics as usual. Stay tuned for the LIVE Republican Debate on September 17th.
Permalink | Email this | Linking Blogs | CommentsProtein Coat might Cure Diabetes
Filed under: Type 2, Adult Onset, Research, Daily News
Researchers found a protein that coats the liver is directly correlated with visceral-fat induced diabetes, or type 2 diabetesWhen visceral fat accumulates, the amount of a hormone called adiponectin, decreases. Adiponectin is found in fat cells, and plays a role in glucose regulation and fatty acid metabolism. Researchers found two types of protein on the surface of mouse liver cells. When the proteins and adiponectin interact, blood sugar and neutral fat levels fall, boosting fat-burning functions. However, obese mice with accumulated visceral fat have fewer of these proteins on the surface of their liver cells. When these proteins increased in number, blood sugar levels would decline. The study hypothesizes that if the quantity of adiponectin decreases in obese people, a potential cure for type 2 diabetes may be found by increasing the proteins found on the surface of the liver.
Talk about the power of protein! We've all heard about the leaders in the pack when it comes to dropping pounds - eggs, fish, chicken, soy and whey protein. But this discovery reveals a new way to combat the bulge and reduce your chances of developing type 2 diabetes. Although these new proteins won't find accommodations in your local grocery store - perhaps Big Pharma will have a designer label to sport in the near future. You'd buy it, wouldn't you?
Top rated diabetes books - what's yours?
Filed under: Type 1, Type 2, Childhood, Adult Onset, Books, Support
TuDiabetes.com is a site for people touched by diabetes. The creator of the site, Manny Hernandez, got the ball rolling on a topic of interest we all take to heart - diabetes book recommendations.
When you ask diabetics to brainstorm on a terribly intrinsic topic you get some pretty good responses. One suggested read was The Diabetes Improvement Program. This book helped a diabetic overcome depression, when the talented team of healthcare professionals could not. Other honorable mentions include: Psyching Out Diabetes, Dr. Bernstein's' Diabetes Solution, Diabesity, and Diabetes for Dummies.
Somebody actually asked something very interesting - where is the book on the evolution of diabetes treatment? Often a topic of discussion, and yet so rarely documented is the sequential events of diabetes treatment, starting with the discovery of insulin. A lull ensued from about 1930 till the boom of genetically modified human insulin, in the early 80s. Any investigative journalist willing to take a stab at it? I guarantee the book will make my must read. And Eli Lilly might actually pay you not to write it.
P.S. One reader pointed out - a chapter of Brent Hoadley's book, Too Profitable to Cure presented a chronology of the evolution of diabetes treatment.
Bark once for yes: training dogs to detect hypos
Filed under: Type 1, Type 2, Research, Daily News
Bad headline for the week: "Does Diabetes Have a Canine Cure?" This, from the Lincolnshire Echo in the UK. Well, no. Of course dogs can't cure diabetes! However, they can do more than just roll their lovable brown eyes at you. Specifically, dogs can be trained to detect building hypoglycemic episodes caused by perilously low blood sugar levels. Dogs that have received such training will then try and sound the alert in various ways like pawing and whining, or pouring you a glass of orange juice (joke). Heck, I think there was even one dog that was trained to dial 911 for his owner, and saved the guy from going into a coma, might I add.This is what this Echo article is really all about. Professors and students at the University of Lincoln have set out to examine the use of dogs to predict hypos. The study is being run in conjunction with Queen's University in Belfast, and has received funding from Diabetes UK. Says research team member Dr. Niro Siriwardena, "We are not yet sure whether dogs detect this [hypos] by smell or because they are much more adept than humans in detecting change. That is something we are looking into."
Stay tuned for details when this study is complete. "Dog people" like myself will be excited to hear what they discover. Wouldn't you like to know what enables dogs to be so super-sensitive? And doesn't it make you wonder: if dogs can detect something like low blood sugar, what else are they noticing about us as we go (obliviously) about our daily lives?
Should you seek a dietician over a doctor?
Filed under: Type 2, Adult Onset, Diet, Research, Opinion, Services, Allie Beatty, Support, Care, Personalities
Thomas Smith began reviewing scientific literature after conventional medicine failed him in controlling diabetes. Smith found research that shows dietary toxins impair cell membrane function. These toxins include trans fatty acids and refined sugars. Cells begin to have trouble absorbing nutrients, and the blood sugar rises. Over time, this results in chronic elevated blood and urine sugar levels. Sounds like a growing epidemic, doesn't it?
This damage to cell membranes, caused by a poor diet, can be repaired. The diabetic syndrome can be cured by eliminating all processed fats and oils. The protocol calls for supplementing high-dose Omega-3 fatty acids. This protocol normalizes blood sugars because the body is continuously repairing cell membranes by using the fats and oils available in the diet. One caution: the speed of recovery is related to the length of the illness. Some Type 2 diabetics may require up to one year for dramatic reductions in blood sugar.
A gaping hole exists between conventional medicine and diet. Conventional medicine claims that the cause of Type 2 diabetes is unknown. Medical doctors, as practitioners of conventional medicine, are not trained to explain how it happened. They treat symptoms with medicine. The business of medicine is medicine. The business of diabetes would be devasted if the cure was as simple as diet. The explanation Thomas Smith provides in his empirical studies is fascinating and I encourage anybody with competing or supporting evidence to open the debate.
This Little Piggy Left the Market
Filed under: Type 1, Childhood, Adult Onset, Lifestyle, Drugs, Research, Opinion, Support
A study published in 1991, comparing the efficacy of human synthetic insulin to porcine insulin states "there is no reason to treat all insulin-requiring diabetic subjects with human insulin except those who have developed insulin allergy".
In light of this study - how was rDNA synthetic human insulin able to monopolize the US market?
The absence of highly purified porcine insulin in the US is probably (my guess) because it's cheaper to manufacture. The saturation of the US market with rDNA synthetic human insulin seems to be treating the masses with a specialized need existing in only a few individuals. But the top line of this marketing campaign must have had a good effect on the bottom-line, too. Sales reps convinced doctors to switch their patients because it was going to become nearly impossible to continue getting animal derived insulin. The insurance companies (the guys picking up the tab) must've loved this option, too. Why wouldn't they? It's better - right?
I'm going to do a self-analysis of the stuff, based on my IAA, IA and C-peptide levels. I've been on human synthetic insulin since 1985. I've never been on highly purified porcine insulin. The IAA is my insulin autoantibodies -- the antibody attacking my islets. My IA is the insulin antibody attacking the injected insulin and my c-peptide will tell me how much insulin my body is making. After 12 weeks on the highly purified porcine insulin - I'm going to do my labs again. I'm curious to see if these levels move, at all. If my c-peptide levels rise, that's a GOOD indicator what's best for Allie Beatty.
So is the best choice for me the best choice for all? Probably not. But at least I can see for myself - even if it costs me a pretty penny to get my hands on highly purified porcine insulin. Nobody said being an experimentalist was cheap. However, never exploring my options would deeply discount the value of experience.
Novocell - A stem cell engineering company
Filed under: Type 1, Childhood, Drugs, Research, Services, Support
Novocell is the first company to use polyethylene glycol (PEG) to encapsulate clusters of insulin-producing cells. This biocompatible substance allows glucose and insulin to pass freely through the coating while preventing the body's immune system from destroying the islets.
The encapsulated islets release human insulin through natural mechanisms in response to the recipient's blood glucose. The islet cells used in this study are isolated from human cadavers. The implant procedure is performed under local anesthesia and the encapsulated islets are injected into a surgically formed micropocket in the subcutaneous tissues of the thigh or lower abdomen of the recipient. The patients received temporary low dose cyclosporine (50-100 ng/ml 12hr trough) and did not receive any other form of immunosuppression.
At the American Diabetes Association 66th Annual Scientific Session in June -- Novocell announced the progress of the study. No adverse events had occurred -- no news is good news. In addition, the company also has the fortune of existing in California - where they can prosper on further stem cell research. Novocell has developed a process that efficiently converts human embryonic stem cells into insulin-producing cells. Novocell believes this study will demonstrate the safety and efficacy of the encapsulation technology that can be used with the unlimited source of insulin-producing cells developed from stem cells to treat patients with diabetes.
Mapping Diabetes
Filed under: Type 2, Adult Onset, Diet, Lifestyle, Research, Daily News
Scientists have mapped the genes responsible for causing type 2 diabetes. This new research is giving hope to new tests that can predict an individuals risk for developing the disease and future treatments.
The study compared the genetic make-up of 700 people with type 2 diabetes and a family history of the condition, with 700 diabetes-free people. Four points on the gene map linked to a person's diabetes risk and were confirmed with another group of 5,000 type 2 diabetics. The findings of this research could explain up to 70% of the genetics related to developing diabetes. A particular zinc transporter, known as SLC30A8, which regulates insulin secretion, was shown to have a mutation. Researchers feel they may be able to treat some cases of diabetes by correcting this mutation.
These findings will allow for the creation of a genetic test to predict people's risk of developing type 2 diabetes, as well as better treatments for the presiding cause of their diabetes. Nary a day passes that I am not motivated for the future of all diabetics. This is the type of research that strengthens my faith in the coming of a cure. Identify the nature of the problem and nip it in the bud.