Heart health and family history
Filed under: Family history, Prevention
When we first applied for life insurance, my marathon running husband was shocked to find out that his premium would be twice as high as mine. The reason, according to our agent, was his strong family history of early heart disease. Though we knew that genetics play a role, we thought that a healthy lifestyle would balance things out. Not so, at least in the eyes of life insurance companies.A healthy lifestyle does have a significant impact on your heart health, but if you've been wondering just how much of a role family history plays in your personal risk of cardiovascular disease, check out this article from WebMD. It covers the basics of family history and may help initiate a conversation about prevention with your doctor.
Prevention zeroes in on families of heart disease sufferers
Filed under: Family history, Prevention
Earlier this year, my great-aunt passed away suddenly from an unknown heart condition. Her doctor recommended that all of her siblings, children, and nieces and nephews be screened for heart problems as well, flagging them at a higher risk for developing cardiovascular disease. Thankfully, no problems were uncovered, but they are now aware of the higher risk associated with having heart disease in our family.Scottish researchers believe that if family members of those with known heart disease were singled out as high-risk and their risk factors gotten under control, up to 40% of early deaths from cardiac events could be prevented. Even so, this type of flagging system is rarely used, even though it is common procedure among families with genetic cancers.
So if someone in your family has had some form of heart disease or heart attack, be sure that you know your risks. Talk to your doctor and tackle any problems that increase your chances of developing cardiovascular disease, such as high cholesterol and high blood pressure, and protect your heart for the long haul.
Genes found that predict heart disease
Filed under: Family history, Research
Scientists in Europe have just found 6 specific genes that may be a key to heart disease. Data shows that people with variations in one or more of these genes have a much greater risk of suffering a heart attack or heart disease before the age of 66. These genes only seem to predict risk, however, not the definite future. Not everyone identified with a "genetic predisposition" ultimately gets sick, so it's still very much worthwhile to eat a heart healthy diet and get plenty of exercise.
[RESEARCH] Long term prognosis in preschool children with wheeze: longitudinal postal questionnaire study 1993-2004
Objectives To follow a population of preschool children with and without parent reported wheeze over a period of 6-11 years to determine prognosis and its important predictive factors.
Design Longitudinal series of five postal surveys based on the international study of asthma and allergies in childhood questionnaire carried out between 1993 and 2004.
Setting Two general practice populations, south Manchester.
Participants 628 children aged less than 5 years at recruitment and those with at least six years’ follow-up data.
Main outcome measures Parent completed questionnaire data for respiratory symptoms and associated features.
Results Of 628 children included in the study, 201 (32%) had parent reported wheeze at the first observation (baseline), of whom 27% also reported the symptom on the second occasion (persistent asthma). The only important baseline predictors of persistent asthma were exercise induced wheeze (odds ratio 3.94, 95% confidence interval 1.72 to 9.00) and a history of atopic disorders (4.44, 1.94 to 10.13). The presence of both predictors indicated a likelihood of 53.2% of developing asthma; if only one feature was present this decreased to 17.2%, whereas if neither was present the likelihood was 10.9%. Family history of asthma was not predictive of persistent asthma among children with preschool wheeze.
Conclusion Using two simple predictive factors (baseline parent reported exercise induced wheeze and a history of atopic disorders), it is possible to estimate the likelihood of future asthma in children presenting with preschool wheeze. The absence of baseline exercise induced wheeze and a history of atopic disorders reduces the likelihood of subsequent asthma by a factor of five.
Flu or a heart attack
Filed under: Prevention, Women Heart Health
Nausea, vomiting and abdominal pain are symptoms of many conditions. During this flu season, don't just disregard your stomach illness as the flu and don't just pass it off as bad food that you ate. A lesson that I learned first hand from my doctor after my flu like symptoms kept coming and going. Conversations with my doctor about personal and family medical history, stress, and ongoing symptoms prompted her to order tests I thought were a little abnormal since I thought I had the flu. These upcoming tests opened my eyes and curiosity to hop on the Internet to do more research. I personally have battled cancer and my whole family has a large history of cancer, heart disease and diabetes. So with this in mind, my doctor has ordered up several tests to determine nothing else is wrong besides the nasty flu bug. With my personal cancer and lupus medical history and my family heart disease and diabetes medical history, the tests make more sense to me now.The obvious diagnosis of most nausea and vomiting is food poisoning. Nausea or vomiting one to eight hours after a meal may indicate food poisoning. However, certain food born bacteria, such as salmonella, can take longer to produce symptoms. If you are a woman and are pregnant, you experience nausea and vomiting. A viral infection such as the flu can induce vomiting and another well known cause for vomiting is ulcers.
Now a little awareness for the not so obvious reasons for vomiting and nausea. Heart attacks, gastroparesis (most common in diabetics), and certain cancers. Coronary artery disease is the leading cause of death and disability in women after menopause and symptoms of a heart attack at times can be vague and mild in women and include nausea and vomiting. Gastroparesis means paralysis of the muscles of the stomach. Gastroparesis results in delayed emptying of food from the stomach into the small intestine and can cause one to have extreme nausea and vomiting. Certain types of cancers like stomach cancer can cause nausea, vomiting, and abdominal pain.
So if you have persistent indigestion, nausea and vomiting off and on, don't just take it for granted that you have food poisoning or the stomach flu. Talk to your doctor about ongoing symptoms that you are experiencing so that they can get to the root of the problem better and give you a more thorough diagnosis.Permalink | Email this | Linking Blogs | Comments
Young women need to pay attention to their hearts too
Filed under: Diet, Family history, Prevention, Research, Exercise, Women Heart Health
Recently, a friend of mine went to the ER with pain in her left shoulder and shortness of breath. I'm too young for heart disease, she said to me when I called to check on her. But they soon had admitted her overnight for some tests, and though thankfully everything was fine, we both learned a lesson that day. We may be young at heart, but we aren't too young for heart disease. Cardiovascular disease is the leading cause of death in women over the age of 25 and it takes more lives than all cancers combined in that age group. I was astonished by that fact. Though women under 50 are less likely to have a heart attack than men, they are more likely to die from them -- likely because women's symptoms can be vague and because women also tend to ignore them. Though those statistics may concern you, there are steps you can take to keep your ticker ticking in a healthy way. Check out this article from Women's Health Magazine that'll give you eight steps you to a healthy heart. There's a ton of good information there, including specific screening tests you can ask for at your next doctor's visit.
[RESEARCH] Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort study
Objective To assess the relation between adherence to a Mediterranean diet and the incidence of diabetes among initially healthy participants.
Design Prospective cohort study with estimates of relative risk adjusted for sex, age, years of university education, total energy intake, body mass index, physical activity, sedentary habits, smoking, family history of diabetes, and personal history of hypertension.
Setting Spanish university department.
Participants 13 380 Spanish university graduates without diabetes at baseline followed up for a median of 4.4 years.
Main outcome measures Dietary habits assessed at baseline with a validated 136 item food frequency questionnaire and scored on a nine point index. New cases of diabetes confirmed through medical reports and an additional detailed questionnaire posted to those who self reported a new diagnosis of diabetes by a doctor during follow-up. Confirmed cases of type 2 diabetes.
Results Participants who adhered closely to a Mediterranean diet had a lower risk of diabetes. The incidence rate ratios adjusted for sex and age were 0.41 (95% confidence interval 0.19 to 0.87) for those with moderate adherence (score 3-6) and 0.17 (0.04 to 0.75) for those with the highest adherence (score 7-9) compared with those with low adherence (score <3). In the fully adjusted analyses the results were similar. A two point increase in the score was associated with a 35% relative reduction in the risk of diabetes (incidence rate ratio 0.65, 0.44 to 0.95), with a significant inverse linear trend (P=0.04) in the multivariate analysis.
Conclusion Adherence to a Mediterranean diet is associated with a reduced risk of diabetes.
Mapping Diabetes
Filed under: Type 2, Adult Onset, Diet, Lifestyle, Research, Daily News
Scientists have mapped the genes responsible for causing type 2 diabetes. This new research is giving hope to new tests that can predict an individuals risk for developing the disease and future treatments.
The study compared the genetic make-up of 700 people with type 2 diabetes and a family history of the condition, with 700 diabetes-free people. Four points on the gene map linked to a person's diabetes risk and were confirmed with another group of 5,000 type 2 diabetics. The findings of this research could explain up to 70% of the genetics related to developing diabetes. A particular zinc transporter, known as SLC30A8, which regulates insulin secretion, was shown to have a mutation. Researchers feel they may be able to treat some cases of diabetes by correcting this mutation.
These findings will allow for the creation of a genetic test to predict people's risk of developing type 2 diabetes, as well as better treatments for the presiding cause of their diabetes. Nary a day passes that I am not motivated for the future of all diabetics. This is the type of research that strengthens my faith in the coming of a cure. Identify the nature of the problem and nip it in the bud.
History underway in type 1 diabetes cure
Filed under: Type 1, Childhood, Research, Events, Support
Dr. Faustman's lab is currently collecting blood samples from individuals with established Type 1 diabetes. These samples are being used to quantify the number of autoreactive T-cells and develop the adequate dosage for Phase 1 of human trials to cure Type 1 diabetes.
The research has been presented and the NIH confirmed it. By reeducating the confused T-cells and instructing them not to attack healthy islets, an apparent cure of established type 1 diabetes in non-obese diabetic mice is possible. Now, Dr. Faustman is collecting human samples to bestow the same cure for diabetes in humans.
If you wish to be a part of this revolutionary event for curing Type 1 diabetes, please contact the Clinical Coordinator or call Dr. Faustman's lab at (617) 726-4084. Each participant is asked to bring a control person along with them - an unrelated person without Type 1 diabetes or another autoimmune disease. Diabetic or not - you can be a part of history in curing Type 1 diabetes!
Swimmer and her insulin pump make history
Filed under: Type 1, Type 2, Childhood, Adult Onset, Lifestyle, Exercise, Daily News, Support
A female swimmer from Nova Scotia made history yesterday morning. Jennifer Alexander, a 32-year-old veteran distance swimmer, completed a round trip swim of the Northumberland Strait between New Brunswick and PEI in less than a day.
Ms. Alexander has diabetes and wanted to raise awareness of the disease. She dove into the Northumberland Strait Wednesday around 9:00 a.m., returning early Thursday morning. No small task, this 26-kilometer swim took a little less than 20 hours (a tad over 16 miles). My fifth grade math textbook projected the United States would switch to metric by 1980. What a crock.
Jennifer was pretty wet, but her waterproof insulin pump stayed dry. The Strait is at its warmest in July, a chilly 16 degrees Celsius -- 60.8 degrees Fahrenheit to us Americans. Jennifer checked her blood sugar about every half hour during the swim. She is gunning for the English Channel in 2009. Love it!
Hey Jennifer, make sure you negotiate a sizable testimonial advertising contract with your insulin pump manufacturer before the Channel. A big congratulations on your stellar accomplishment. Anything is possible with diabetes, especially for athletes. Don't miss Diane's earlier post on technology advances to keep athletes with diabetes in the game.